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NSC

XCell manufactures our neural stem cells using the Rosette methodology  and expands to a defined passage for each lot. Each lot is compared with previous lots to ensure consistency of the product and ensure reproducibility for your experiments. Our comprehensive analysis include microarray analysis of gene expression, PCR and immunocytochemistry as well as assessing differentiation into neurons and astrocytes. The cells are supplied with medium optimized  for the  propagation of the cells. Cells can be expanded for a limited number of passages  without affecting their ability for tri-lineage differentiation.
 
Neurons derived from these NSC express cortical positional markers. To derive dopaminergic neurons or spinal  motoneurons from NSC please discuss with our service representative 

Control Lines

Product Description Reprogram Method Source
XCL-1 Male Control Line Episomal Vectors Cord blood cells CD34+
XCL-6 Female Control Line Episomal Vectors Cord blood cells CD34+

Knockout Lines

Product Description Associated Disease Parental Line
SOD1-/- Custom Request ALS XCL-1
SOD1+/- Custom Request ALS XCL-1
APOE-/- Custom Request Alzheimer's Disease XCL-1
CNTNAP2-/- Custom Request Autism XCL-1
CNTNAP2 +/- Custom Request Autism XCL-1
BDNF-/- Custom Request CNS in General XCL-1
BDNF+/- Custom Request CNS in General XCL-1
LRRK2-/- Custom Request Parkinson's Disease XCL-1
LRRK2+/- Custom Request Parkinson's Disease XCL-1
PARK2-/- Custom Request Parkinson's Disease XCL-1
PARK2+/- Custom Request Parkinson's Disease XCL-1
PINK1 -/- Custom Request Parkinson's Disease XCL-1
PINK1+/- Custom Request Parkinson's Disease XCL-1
PARK7-/- Custom Request Parkinson's Disease XCL-1
PARK7+/- Custom Request Parkinson's Disease XCL-1
PARK2-/-;PINK1-/- Custom Request Parkinson's Disease XCL-1
PARK2-/-;PARK7-/- Custom Request Parkinson's Disease XCL-1
DISC1-/- Custom Request Schizophrenia XCL-1

Reporter Lines

Product Description Parental Line
AAVS-DCX-GFP Custom Request XCL-1
CAG-GFP-chr13-hetero Custom Request XCL-1
CAG-GFP13-RFP19-hetero Custom Request XCL-1
CAG-GFP-chr19-homo Custom Request XCL-1
CAG-GFP-chr19-hetero Custom Request XCL-1
GFAP-NanolucHalotag-hetero Custom Request XCL-1
MAP2-NanolucHalotag-hetero Custom Request XCL-1